MeSH Browser

MeSH Heading: Herpesvirus 6, Human
Tree Number(s): B04.280.382.150.750.400
Unique ID: D015654
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015654
Annotation: infection: coordinate IM with ROSEOLOVIRUS INFECTIONS (IM) but consider also EXANTHEMA SUBITUM
Scope Note: Members of the ROSEOLOVIRUS genus of the Betaherpesvirales subfamily isolated from patients with AIDS and other LYMPHOPROLIFERATIVE DISORDERS. It infects and replicates in fresh and established lines of hematopoietic cells and cells of neural origin. It also appears to alter the activity of NK CELLS. HHV-6; (HBLV) antibodies are elevated in patients with AIDS; SJOGREN'S SYNDROME; SARCOIDOSIS; CHRONIC FATIGUE SYNDROME, and certain malignancies. HHV-6A is the most common cause of EXANTHEMA SUBITUM and has been implicated in encephalitis. When HHV-6 integrates into the host genome it is referred to as ciHVH-6. When such VIRUS INTEGRATION occurs into the germline it is referred to as iciHHV-6.
Entry Version: HHV 6
Entry Term(s): Chromosomally Integrated Human Herpesvirus 6; Chromosomally Integrated Human Herpesvirus 6A; Chromosomally Integrated Human Herpesvirus 6B; HBLV; HHV-6; HHV-6A; HHV-6B; HHV6; HHV6A; HHV6B; Herpesvirus 6A, Human; Herpesvirus 6B, Human; Human B-Lymphotropic Virus; Human Herpesvirus 6; Human betaherpesvirus 6; Human betaherpesvirus 6A; Human betaherpesvirus 6B; Inherited Chromosomally Integrated Human Herpesvirus 6; Inherited Chromosomally Integrated Human Herpesvirus 6A; Inherited Chromosomally Integrated Human Herpesvirus 6B; ciHHV-6; ciHHV-6A; ciHHV-6B; ciHHV6; ciHHV6A; ciHHV6B; iciHHV-6; iciHHV-6A; iciHHV-6B; iciHHV6; iciHHV6A; iciHHV6B
Registry Numbers: txid10368
Previous Indexing: Herpesviridae (1986-1989)
See Also: Exanthema Subitum
Public MeSH Note: 94; was HERPESVIRUS-6, HUMAN 1990-93; HUMAN HERPESVIRUS-6 was see HERPESVIRUS-6, HUMAN 1990-93
Online Note: use HERPESVIRUS 6, HUMAN to search HERPESVIRUS-6, HUMAN & HUMAN HERPESVIRUS-6 1990-93
History Note: 94; was HERPESVIRUS-6, HUMAN 1990-93; HUMAN HERPESVIRUS-6 was see HERPESVIRUS-6, HUMAN 1990-93
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2020/09/02

Allowable Qualifiers: chemistry (CH)

classification (CL)

drug effects (DE)

enzymology (EN)

genetics (GE)

growth & development (GD)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pathogenicity (PY)

physiology (PH)

radiation effects (RE)

ultrastructure (UL)

Viruses [B04]
- DNA Viruses [B04.280]
  - Herpesviridae [B04.280.382]
    - Betaherpesvirinae [B04.280.382.150]
      - Roseolovirus [B04.280.382.150.750]
        
        Herpesvirus 6, Human [B04.280.382.150.750.400]
        
        Herpesvirus 7, Human [B04.280.382.150.750.420]

Herpesvirus 6, Human Preferred

Concept UI: M0023992
Registry Numbers: txid10368
Scope Note: Members of the ROSEOLOVIRUS genus of the Betaherpesvirales subfamily isolated from patients with AIDS and other LYMPHOPROLIFERATIVE DISORDERS. It infects and replicates in fresh and established lines of hematopoietic cells and cells of neural origin. It also appears to alter the activity of NK CELLS. HHV-6; (HBLV) antibodies are elevated in patients with AIDS; SJOGREN'S SYNDROME; SARCOIDOSIS; CHRONIC FATIGUE SYNDROME, and certain malignancies. HHV-6A is the most common cause of EXANTHEMA SUBITUM and has been implicated in encephalitis. When HHV-6 integrates into the host genome it is referred to as ciHVH-6. When such VIRUS INTEGRATION occurs into the germline it is referred to as iciHHV-6.
Terms: Herpesvirus 6, Human Preferred Term
Term UI T046311
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); HBLV
Term UI T046309
Date02/02/1989
LexicalTag ABB
ThesaurusID NLM (1990); HHV-6
Term UI T046312
Date04/28/1989
LexicalTag ABB
ThesaurusID NLM (1990); Human B-Lymphotropic Virus
Term UI T046313
Date02/02/1989
LexicalTag NON
ThesaurusID NLM (1990); HHV6
Term UI T000878351
Date04/17/2015
LexicalTag NON
ThesaurusID NLM (2016); Human Herpesvirus 6
Term UI T000882407
Date06/24/2015
LexicalTag NON
ThesaurusID NLM (2002); Human betaherpesvirus 6
Term UI T000912133
Date11/28/2016
LexicalTag NON
ThesaurusID NLM (2018)

Herpesvirus 6A, Human Narrower

Concept UI: M0360230
Scope Note: Strain of HHV-6 VIRUS that is commonly seen in patients affected by MULTIPLE SCLEROSIS and other neurological diseases.
Terms: Herpesvirus 6A, Human Preferred Term
Term UI T436367
Date02/15/2001
LexicalTag NON
ThesaurusID NLM (2002); HHV-6A
Term UI T411407
Date04/07/2000
LexicalTag ACR
ThesaurusID NLM (2001); HHV6A
Term UI T000878352
Date04/17/2015
LexicalTag NON
ThesaurusID NLM (2016); Human betaherpesvirus 6A
Term UI T000912134
Date11/28/2016
LexicalTag NON
ThesaurusID NLM (2018)

Herpesvirus 6B, Human Narrower

Concept UI: M0360231
Scope Note: Strain of HHV-6 VIRUS that primarily occurs in infants and causes a rash and fever. This strand is also common in transplant patients.
Terms: Herpesvirus 6B, Human Preferred Term
Term UI T436368
Date02/15/2001
LexicalTag NON
ThesaurusID NLM (2002); HHV-6B
Term UI T411408
Date04/07/2000
LexicalTag ACR
ThesaurusID NLM (2001); HHV6B
Term UI T000878353
Date04/17/2015
LexicalTag NON
ThesaurusID NLM (2016); Human betaherpesvirus 6B
Term UI T000912135
Date11/28/2016
LexicalTag NON
ThesaurusID NLM (2018)

Chromosomally Integrated Human Herpesvirus 6 Narrower

Chromosomally Integrated Human Herpesvirus 6A Narrower

Chromosomally Integrated Human Herpesvirus 6B Narrower

Inherited Chromosomally Integrated Human Herpesvirus 6 Narrower

Inherited Chromosomally Integrated Human Herpesvirus 6A Narrower

Inherited Chromosomally Integrated Human Herpesvirus 6B Narrower

Herpesvirus 6, Human MeSH Descriptor Data 2025