NLM Logo

Fatigue Syndrome, Chronic MeSH Descriptor Data 2025


MeSH Heading
Fatigue Syndrome, Chronic
Tree Number(s)
C05.651.310
C10.586.500.600
C10.668.364
C23.550.291.500.392
Unique ID
D015673
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015673
Annotation
a clinical entity: do not confuse with "chronic fatigue" (= FATIGUE + CHRONIC DISEASE (NIM))
Scope Note
A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
Entry Term(s)
Chronic Fatigue Disorder
Chronic Fatigue Syndrome
Chronic Fatigue and Immune Dysfunction Syndrome
Chronic Fatigue-Fibromyalgia Syndrome
Encephalomyelitis, Myalgic
Infectious Mononucleosis-Like Syndrome, Chronic
Myalgic Encephalomyelitis
Postviral Fatigue Syndrome
Royal Free Disease
Systemic Exertion Intolerance Disease
Previous Indexing
Encephalomyelitis (1966-1989)
Fatigue (1977-1989)
Muscular Diseases (1966-1989)
Virus Diseases (1986-1989)
See Also
Fibromyalgia
Public MeSH Note
90
History Note
90
Date Established
1990/01/01
Date of Entry
1989/05/25
Revision Date
2023/04/05
Fatigue Syndrome, Chronic Preferred
page delivered in 0.179s