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Receptors, Leukocyte-Adhesion MeSH Descriptor Data 2022


MeSH Heading
Receptors, Leukocyte-Adhesion
Tree Number(s)
D12.776.543.750.705.408.600
Unique ID
D016028
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016028
Scope Note
Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells.
Entry Version
RECEPT LEUKOCYTE ADHESION
Entry Term(s)
Leu-CAM Receptor Family
Leukocyte-Adhesion Receptor
Leukocyte-Adhesion Receptor Family
Leukocyte-Adhesion Receptors
Registry Number
0
Previous Indexing
Antigens (1966-1987)
Antigens, Differentiation (1988-1989)
Receptors, Cell Surface (1973-1989)
Receptors, Immunologic (1980-1989)
See Also
Leukocyte-Adhesion Deficiency Syndrome
Public MeSH Note
90
History Note
90
Date Established
1990/01/01
Date of Entry
1989/07/07
Revision Date
2003/07/09
Receptors, Leukocyte-Adhesion Preferred
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