MeSH Browser

MeSH Heading: Integrin beta Chains
Tree Number(s): D12.776.543.750.705.408.200
Unique ID: D039641
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D039641
Scope Note: Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.
Entry Term(s): Integrin beta Subunits; beta Integrins
Previous Indexing: Integrins (1990-2002)
Public MeSH Note: 2003
History Note: 2003
Date Established: 2003/01/01
Date of Entry: 2002/07/02
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0419369
Scope Note: Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.
Terms: Integrin beta Chains Preferred Term
Term UI T488260
Date04/01/2002
LexicalTag NON
ThesaurusID NLM (2003); beta Integrins
Term UI T490020
Date04/18/2002
LexicalTag NON
ThesaurusID NLM (2003); Integrin beta Subunits
Term UI T493910
Date05/15/2002
LexicalTag NON
ThesaurusID NLM (2003)

Integrin beta Chains MeSH Descriptor Data 2024