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Granulocyte-Macrophage Colony-Stimulating Factor MeSH Descriptor Data 2022


MeSH Heading
Granulocyte-Macrophage Colony-Stimulating Factor
Tree Number(s)
D12.644.276.374.410.240.375
D12.776.395.240.300
D12.776.467.374.410.240.375
D23.529.374.410.240.375
Unique ID
D016178
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016178
Scope Note
An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
Entry Version
GMCSF
Entry Term(s)
CSF-2
CSF-GM
Colony-Stimulating Factor, Granulocyte-Macrophage
GM-CSF
Histamine-Producing Cell-Stimulating Factor
TC-GM-CSF
Tumor-Cell Human GM Colony-Stimulating Factor
Registry Number
83869-56-1
CAS Type 1 Name
Colony-stimulating factor 2
Previous Indexing
Colony-Stimulating Factors (1976-1990)
Growth Substances (1966-1990)
Interleukin-3 (1981-1987)
See Also
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
Public MeSH Note
91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91
Online Note
use INTERLEUKIN-3 to search HISTAMINE-PRODUCING CELL-STIMULATING FACTOR 1987-91
History Note
91; HISTAMINE-PRODUCING CELL-STIMULATING FACTOR was HISTAMINE-PRODUCING CELL STIMULATING FACTOR see INTERLEUKIN-3 1987-91
Date Established
1991/01/01
Date of Entry
1990/06/19
Revision Date
2006/07/05
Granulocyte-Macrophage Colony-Stimulating Factor Preferred
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