NLM Logo

Granulocyte Colony-Stimulating Factor MeSH Descriptor Data 2022


MeSH Heading
Granulocyte Colony-Stimulating Factor
Tree Number(s)
D12.644.276.374.410.240.350
D12.776.395.240.200
D12.776.467.374.410.240.350
D23.529.374.410.240.350
Unique ID
D016179
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016179
Scope Note
A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.
Entry Version
GCSF
Entry Term(s)
G-CSF
Registry Number
143011-72-7
CAS Type 1 Name
Colony-stimulating factor, granulocyte
NLM Classification #
WH 200
Previous Indexing
Colony-Stimulating Factors (1976-1990)
See Also
Receptors, Granulocyte Colony-Stimulating Factor
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/06/19
Revision Date
2011/06/24
Granulocyte Colony-Stimulating Factor Preferred
page delivered in 0.15s