- Concept UI
- M0024768
- Registry Numbers
- 104781-85-3
- Scope Note
- A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
- Terms
-
Fibroblast Growth Factor 1
Preferred Term
Term UI
T440828
Date03/27/2001
LexicalTag
NON
ThesaurusID
NLM (2002)
-
Acidic Fibroblast Growth Factor
Term UI
T048283
Date03/01/1990
LexicalTag
NON
ThesaurusID
NLM (1991)
-
Class I Heparin-Binding Growth Factor
Term UI
T048281
Date03/01/1990
LexicalTag
NON
ThesaurusID
NLM (1991)
-
FGF-1
Term UI
T326073
Date01/01/1955
LexicalTag
ACR
ThesaurusID
NLM (2002)
-
FGF1
Term UI
T326074
Date01/01/1955
LexicalTag
ACR
ThesaurusID
NLM (2002)
-
Fibroblast Growth Factor, Acidic
Term UI
T048284
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1991)
-
Fibroblast Growth Factor-1
Term UI
T326075
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2002)
-
Heparin-Binding Fibroblast Growth Factor Class I
Term UI
T048286
Date03/01/1990
LexicalTag
NON
ThesaurusID
NLM (1991)
-
HBGF-1
Term UI
T048285
Date03/01/1990
LexicalTag
ACR
ThesaurusID
NLM (1991)
-
Heparin-Binding Growth Factor, Class I
Term UI
T048282
Date03/01/1990
LexicalTag
NON
ThesaurusID
NLM (1991)