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Fibroblast Growth Factor 1 MeSH Descriptor Data 2022


MeSH Heading
Fibroblast Growth Factor 1
Tree Number(s)
D12.644.276.624.110
D12.776.467.624.110
D23.529.624.110
Unique ID
D016220
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016220
Scope Note
A 17-kDa single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. It binds to HEPARIN, which potentiates its biological activity and protects it from proteolysis. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages, and also has chemotactic and mitogenic activities. It was originally named acidic fibroblast growth factor based upon its chemical properties and to distinguish it from basic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 2).
Entry Term(s)
Acidic Fibroblast Growth Factor
Class I Heparin-Binding Growth Factor
FGF-1
FGF1
Fibroblast Growth Factor, Acidic
Fibroblast Growth Factor-1
HBGF-1
Heparin-Binding Fibroblast Growth Factor Class I
Heparin-Binding Growth Factor, Class I
Registry Number
104781-85-3
CAS Type 1 Name
Fibroblast growth factor (human brain acidic protein moiety reduced)
Previous Indexing
Fibroblast Growth Factor (1984-1990)
Growth Substances (1974-1983)
Public MeSH Note
2002; FIBROBLAST GROWTH FACTOR-1 was indexed under FIBROBLAST GROWTH FACTOR ACIDIC 2001, FIBROBLAST GROWTH FACTOR 2000-2001 & under FIBROBLAST GROWTH FACTOR, BASIC 1998-2000
History Note
2002(1991); for FIBROBLAST GROWTH FACTOR-1 use FIBROBLAST GROWTH FACTOR 1(NM) 1998-2001
Date Established
1991/01/01
Date of Entry
1990/07/05
Revision Date
2006/07/05
Fibroblast Growth Factor 1 Preferred
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