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Aflatoxin B1 MeSH Descriptor Data 2022


MeSH Heading
Aflatoxin B1
Tree Number(s)
D03.383.663.283.119.075
D03.633.100.150.119.075
D23.946.587.142.075
Unique ID
D016604
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016604
Annotation
/antag permitted but consider also ANTITOXINS
Scope Note
A potent hepatotoxic and hepatocarcinogenic mycotoxin produced by the Aspergillus flavus group of fungi. It is also mutagenic, teratogenic, and causes immunosuppression in animals. It is found as a contaminant in peanuts, cottonseed meal, corn, and other grains. The mycotoxin requires epoxidation to aflatoxin B1 2,3-oxide for activation. Microsomal monooxygenases biotransform the toxin to the less toxic metabolites aflatoxin M1 and Q1.
Entry Version
AFB1
Entry Term(s)
Aflatoxin B
Aflatoxin B(1)
Aflatoxin B1 Dihydrochloride, (6aR-cis)-Isomer
Aflatoxin B1, (6aR-cis)-Isomer, 14C-Labeled
Aflatoxin B1, (6aR-cis)-Isomer, 2H-Labeled
Aflatoxin B1, (6aR-cis)-Isomer, 3H-Labeled
Aflatoxin B1, cis(+,-)-Isomer
HSDB-3453
NSC-529592
Pharm Action
Poisons
Registry Number
9N2N2Y55MH
Related Numbers
10279-73-9
1162-65-8
43043-21-6
77076-87-0
77076-88-1
84415-24-7
CAS Type 1 Name
Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)-
Previous Indexing
Aflatoxins (1966-1991)
Public MeSH Note
92; AFLATOXIN B1 was indexed under AFLATOXINS 1980-91
Online Note
use AFLATOXIN B1 (NM) to search AFLATOXIN B1 1979-91
History Note
92; was AFLATOXIN B1 (NM) 1980-91
Date Established
1992/01/01
Date of Entry
1991/01/24
Revision Date
2020/05/27
Aflatoxin B1 Preferred
Aflatoxin B1, (6aR-cis)-Isomer, 3H-Labeled Narrower
Aflatoxin B1, cis(+,-)-Isomer Narrower
HSDB-3453 Narrower
Aflatoxin B1, (6aR-cis)-Isomer, 14C-Labeled Narrower
Aflatoxin B Broader
Aflatoxin B1 Dihydrochloride, (6aR-cis)-Isomer Narrower
Aflatoxin B1, (6aR-cis)-Isomer, 2H-Labeled Narrower
NSC-529592 Narrower
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