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Apolipoprotein A-I MeSH Descriptor Data 2022


MeSH Heading
Apolipoprotein A-I
Tree Number(s)
D10.532.091.200.100
D12.776.070.400.200.100
D12.776.521.120.200.100
Unique ID
D016632
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016632
Scope Note
The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
Entry Term(s)
Apo A-1
Apo A-I
Apo A-I Isoproteins
Apo A1
Apo AI
ApoA-1
ApoA-I
Apolipoprotein A-1
Apolipoprotein A-I Isoprotein-2
Apolipoprotein A-I Isoprotein-4
Apolipoprotein A-I Isoproteins
Apolipoprotein A1
Apolipoprotein AI
Apolipoprotein AI Propeptide
Pro-Apo A-I
Pro-Apolipoprotein A-I
Proapolipoprotein AI
Registry Number
0
Previous Indexing
Apolipoproteins (1977-1984)
Apolipoproteins A (1985-1991)
Public MeSH Note
1992; APOLIPOPROTEIN A-I was indexed under APOLIPOPROTEINS A 1985-1991, under APOLIPOPROTEINS 1979-1984 & under APOPROTEINS 1974-1978; PRO-APOLIPOPROTEIN A-I was indexed under APOLIPOPROTEINS A & PROTEIN PRECURSORS 1983-2006; APOLIPOPROTEIN A-I ISOPROTEINS was indexed under APOLIPOPROTEINS A 1980-2006
History Note
1992 (1974); for PRO-APOLIPOPROTEIN A-I (NM) use APOLIPOPROTEINS A & PROTEIN PRECURSORS 1983-2006; for APOLIPOPROTEIN A-I ISOPROTEINS (NM) use APOLIPOPROTEINS A 1980-2006
Date Established
1992/01/01
Date of Entry
1991/01/24
Revision Date
2006/07/05
Apolipoprotein A-I Preferred
Pro-Apolipoprotein A-I Narrower
Apolipoprotein A-I Isoproteins Narrower
Apolipoprotein A-I Isoprotein-2 Narrower
Apolipoprotein A-I Isoprotein-4 Narrower
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