MeSH Browser

MeSH Heading: Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
Tree Number(s): D08.811.277.450.483.765
Unique ID: D017038
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017038
Scope Note: A group of related enzymes responsible for the endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose-content glycopeptides and GLYCOPROTEINS.
Entry Term(s): Di-N-Acetylchitobiosyl beta-N-Acetylglucosaminidase; ENGASE Protein; Endo D Endoglucosaminidase; Endo F Endoglucosaminidase; Endo H Endoglucosaminidase; Endo-N-Acetyl-beta-d-glucosaminidase; Endo-beta-Acetylglucosaminidase; Endo-beta-N-Acetylglucosaminidase; Endo-beta-N-Acetylglucosaminidase D; Endo-beta-N-Acetylglucosaminidase F; Endo-beta-N-Acetylglucosaminidase H; Endoglucosaminidase D; Endoglucosaminidase F; Endoglucosaminidase H; Endoglucosidase H; Endoglycosidase D; Endoglycosidase F; Endohexosaminidase F; Endohexosaminidase H; Peptide N-Glycosidase F
Registry Numbers: EC 3.2.1.96; EC 3.2.1.96; EC 3.2.1.96; EC 3.2.1.96; EC 3.2.1.96; EC 3.2.1.96
Related Numbers: 37278-88-9
CAS Type 1 Name: Glycopeptide-D-mannosyl-N(4)-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase
Previous Indexing: Acetylglucosaminidase (1986-1991); Glycoside Hydrolases (1979-1985)
Public MeSH Note: 1992; for ENDOGLUCOSAMINIDASE F use GLUCOSAMINIDASE 1987-2004, for ENDOGLUCOSAMINIDASE H use GLUCOSAMINIDASE 1983-2004; for ENDOGLYCOSIDASE D use GLUCOSAMINIDASE 1980-2004; ENDO-BETA-ACETYLGLUCOSAMINIDASE was indexed under ACETYLGLUCOSAMINIDASE 1986-1991 & under GLYCOSIDE HYDROLASES 1979-1985; ENDOGLYCOSIDASE F was indexed under GLYCOSIDE HYDROLASES 1983-1991; ENDOHEXOSAMINIDASE H was indexed under HEXOSAMINIDASES 1982-1992
History Note: 1992 (1979); for ENDOGLUCOSAMINIDASE F use GLUCOSAMINIDASE 1987-2004; for ENDOGLUCOSAMINIDASE H use GLUCOSAMINIDASE 1983-2004; for ENDOGLYCOSIDASE D use GLUCOSAMINIDASE 1980-2004
Date Introduced: 1992/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Glycoside Hydrolases [D08.811.277.450]
      - Hexosaminidases [D08.811.277.450.483]
        
        alpha-N-Acetylgalactosaminidase [D08.811.277.450.483.044]
        
        beta-N-Acetyl-Galactosaminidase [D08.811.277.450.483.112]
        
        beta-N-Acetylhexosaminidases [D08.811.277.450.483.180]
        
        Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase [D08.811.277.450.483.765]

Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase Preferred

Concept UI: M0025885
Registry Numbers: EC 3.2.1.96
Related Numbers: 37278-88-9
Scope Note: A group of related enzymes responsible for the endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose-content glycopeptides and GLYCOPROTEINS.
Terms: Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase Preferred Term
Term UI T050864
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1992); Di-N-Acetylchitobiosyl beta-N-Acetylglucosaminidase
Term UI T050861
Date04/05/1991
LexicalTag NON
ThesaurusID NLM (1992); Endo-beta-Acetylglucosaminidase
Term UI T050862
Date04/05/1991
LexicalTag NON
ThesaurusID NLM (1992); Endo-beta-N-Acetylglucosaminidase
Term UI T001148622
Date05/22/2025
LexicalTag NON
ThesaurusID NLM (2025); Endo-N-Acetyl-beta-d-glucosaminidase
Term UI T050863
Date04/05/1991
LexicalTag NON
ThesaurusID NLM (1992); ENGASE Protein
Term UI T001148623
Date05/22/2025
LexicalTag ABX
ThesaurusID NLM (2025)

Endo-beta-N-Acetylglucosaminidase F Narrower

Concept UI: M0009335
Registry Numbers: EC 3.2.1.96
Terms: Endo-beta-N-Acetylglucosaminidase F Preferred Term
Term UI T050869
Date04/05/1991
LexicalTag NON
ThesaurusID NLM (1992); Endo F Endoglucosaminidase
Term UI T577690
Date03/18/2004
LexicalTag NON
ThesaurusID NLM (2005); Endoglucosaminidase F
Term UI T017998
Date08/10/1987
LexicalTag NON
ThesaurusID UNK (19XX); Endoglycosidase F
Term UI T050868
Date04/09/1991
LexicalTag NON
ThesaurusID NLM (1992); Peptide N-Glycosidase F
Term UI T577689
Date03/18/2004
LexicalTag NON
ThesaurusID NLM (2005)

Endo-beta-N-Acetylglucosaminidase H Narrower

Concept UI: M0009336
Registry Numbers: EC 3.2.1.96
Terms: Endo-beta-N-Acetylglucosaminidase H Preferred Term
Term UI T050867
Date04/05/1991
LexicalTag NON
ThesaurusID NLM (1992); Endo H Endoglucosaminidase
Term UI T577721
Date03/18/2004
LexicalTag NON
ThesaurusID NLM (2005); Endoglucosaminidase H
Term UI T017999
Date09/16/1983
LexicalTag NON
ThesaurusID UNK (19XX); Endoglucosidase H
Term UI T050866
Date04/05/1991
LexicalTag NON
ThesaurusID NLM (1992)

Endohexosaminidase H Narrower

Endo-beta-N-Acetylglucosaminidase D Narrower

Concept UI: M0025886
Registry Numbers: EC 3.2.1.96
Terms: Endo-beta-N-Acetylglucosaminidase D Preferred Term
Term UI T050865
Date04/05/1991
LexicalTag NON
ThesaurusID NLM (1992); Endo D Endoglucosaminidase
Term UI T577720
Date03/18/2004
LexicalTag NON
ThesaurusID NLM (2005); Endoglucosaminidase D
Term UI T577727
Date03/18/2004
LexicalTag NON
ThesaurusID NLM (2005); Endoglycosidase D
Term UI T018001
Date08/01/1980
LexicalTag NON
ThesaurusID UNK (19XX)

Endohexosaminidase F Narrower

Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase MeSH Descriptor Data 2026