NLM Logo

MELAS Syndrome MeSH Descriptor Data 2023


MeSH Heading
MELAS Syndrome
Tree Number(s)
C05.651.460.620.520
C10.228.140.163.100.535
C10.228.140.300.275.500
C10.668.491.500.500.500
C14.907.253.329.500
C16.320.565.189.535
C18.452.132.100.535
C18.452.648.189.535
C18.452.660.560.620.520
Unique ID
D017241
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017241
Scope Note
A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
Entry Term(s)
MELAS
Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes
Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode
Myopathy, Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke
Previous Indexing
Acidosis (1985-1986)
Acidosis, Lactic (1987-1992)
Brain Diseases (1985-1987)
Brain Diseases, Metabolic (1987-1992)
Cerebrovascular Disorders (1987-1992)
Lactates (1985-1986)
Mitochondria, Muscle (1984-1992)
Neuromuscular Diseases (1987-1992)
Public MeSH Note
1993
History Note
1993
Date Established
1993/01/01
Date of Entry
1992/05/22
Revision Date
2013/07/08
MELAS Syndrome Preferred
page delivered in 0.196s