MeSH Browser

MeSH Heading: Myelinolysis, Central Pontine
Tree Number(s): C10.228.140.163.560; C10.314.500; C18.452.132.560
Unique ID: D017590
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017590
Scope Note: A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
Entry Term(s): Central Pontine Myelinolysis; Extrapontine Myelinoclasis; Extrapontine Myelinolysis; Myelinoclasis, Central Pontine; Pontine Myelinolysis, Central
Previous Indexing: Demyelinating Diseases (1966-1993); Pons (1966-1993)
Public MeSH Note: 1994
History Note: 1994
Date Established: 1994/01/01
Date of Entry: 1992/12/28
Revision Date: 2009/07/06

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0026656
Scope Note: A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
Terms: Myelinolysis, Central Pontine Preferred Term
Term UI T052748
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); Myelinoclasis, Central Pontine
Term UI T052745
Date06/18/1992
LexicalTag NON
ThesaurusID NLM (1994); Central Pontine Myelinolysis
Term UI T052746
Date06/29/1992
LexicalTag NON
ThesaurusID; Pontine Myelinolysis, Central
Term UI T052747
Date09/09/1992
LexicalTag NON
ThesaurusID NLM (1994)

Myelinolysis, Central Pontine MeSH Descriptor Data 2024