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Myelinolysis, Central Pontine MeSH Descriptor Data 2022


MeSH Heading
Myelinolysis, Central Pontine
Tree Number(s)
C10.228.140.163.560
C10.314.500
C18.452.132.560
Unique ID
D017590
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017590
Scope Note
A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
Entry Term(s)
Central Pontine Myelinolysis
Extrapontine Myelinoclasis
Extrapontine Myelinolysis
Myelinoclasis, Central Pontine
Pontine Myelinolysis, Central
Previous Indexing
Demyelinating Diseases (1966-1993)
Pons (1966-1993)
Public MeSH Note
1994
History Note
1994
Date Established
1994/01/01
Date of Entry
1992/12/28
Revision Date
2009/07/06
Myelinolysis, Central Pontine Preferred
Extrapontine Myelinolysis Related
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