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Kleine-Levin Syndrome MeSH Descriptor Data 2023


MeSH Heading
Kleine-Levin Syndrome
Tree Number(s)
C10.886.425.800.200.500
F03.870.400.800.200.500
Unique ID
D017593
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017593
Scope Note
A rare condition characterized by recurrent hypersomnias associated with hyperphagia, occurring primarily in males in the second to third decade of life. Clinical features include mental confusion, excessive sleep requirements (approximately 18 hours per day), restlessness, and in some cases hallucinations. Episodes have a duration of days to weeks, and may recur several times per year. This condition may resolve spontaneously over several years. (From Adams, et al., Principles of Neurology, 6th ed, p569)
Entry Term(s)
Familial Hibernation (Kleine-Levin) Syndrome
Familial Kleine-Levin Syndrome
Hypersomnia, Periodic
Kleine-Levin Hibernation Syndrome
Kleine-Levin-Critchley Syndrome
Previous Indexing
Eating Disorders (1966-1976)
Hunger (1966-1971)
Hyperphagia (1981-1993)
Hypersomnia (1975-1993)
Sleep Disorders (1966-1979)
Public MeSH Note
94
History Note
94
Date Established
1994/01/01
Date of Entry
1992/12/28
Revision Date
2012/07/03
Kleine-Levin Syndrome Preferred
Familial Kleine-Levin Syndrome Related
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