A group of symptoms that are two- to three-fold more common in those who work in large, energy-efficient buildings, associated with an increased frequency of headaches, lethargy, and dry skin. Clinical manifestations include hypersensitivity pneumonitis (ALVEOLITIS, EXTRINSIC ALLERGIC); allergic rhinitis (RHINITIS, ALLERGIC, PERENNIAL); ASTHMA; infections, skin eruptions, and mucous membrane irritation syndromes. Current usage tends to be less restrictive with regard to the type of building and delineation of complaints. (From Segen, Dictionary of Modern Medicine, 1992)
Entry Term(s)
Sick House Syndrome
NLM Classification #
WA 754
Previous Indexing
Air Pollution, Indoor (1992-1995)
Environmental Exposure (1990-1991)
Occupational Diseases (1984-1989)
Public MeSH Note
96; was see AIR POLLUTION, INDOOR 1992-95, was see ENVIRONMENTAL EXPOSURE 1990-91
Online Note
use AIR POLLUTION, INDOOR to search SICK BUILDING SYNDROME 1992-95; use ENVIRONMENTAL EXPOSURE 1990-91
History Note
96; was see AIR POLLUTION, INDOOR 1992-95, was see ENVIRONMENTAL EXPOSURE 1990-91
A group of symptoms that are two- to three-fold more common in those who work in large, energy-efficient buildings, associated with an increased frequency of headaches, lethargy, and dry skin. Clinical manifestations include hypersensitivity pneumonitis (ALVEOLITIS, EXTRINSIC ALLERGIC); allergic rhinitis (RHINITIS, ALLERGIC, PERENNIAL); ASTHMA; infections, skin eruptions, and mucous membrane irritation syndromes. Current usage tends to be less restrictive with regard to the type of building and delineation of complaints. (From Segen, Dictionary of Modern Medicine, 1992)