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Insulin-Like Growth Factor Binding Protein 1 MeSH Descriptor Data 2024


MeSH Heading
Insulin-Like Growth Factor Binding Protein 1
Tree Number(s)
D12.776.157.420.250
Unique ID
D018970
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018970
Scope Note
One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
Entry Term(s)
IGF-Binding Protein 1
IGFBP-1
Registry Number
0
Previous Indexing
Carrier Proteins (1992-1995)
Public MeSH Note
2005; see INSULIN-LIKE-GROWTH-FACTOR-BINDING PROTEIN-1 1996-2005; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 was indexed under CARRIER PROTEINS 1992-95
History Note
2005(1992)
Date Established
1996/01/01
Date of Entry
1995/06/08
Revision Date
2013/07/09
Insulin-Like Growth Factor Binding Protein 1 Preferred
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