Staurosporine MeSH Descriptor Data 2024

MeSH Heading: Staurosporine
Tree Number(s): D03.132.436.750; D03.633.100.473.144.750; D03.633.100.473.402.750; D03.633.100.496.500.500.750; D03.633.300.148.750
Unique ID: D019311
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019311
Scope Note: An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Entry Term(s): 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
Pharm Action: Enzyme Inhibitors
Related Numbers: 62996-74-1
Previous Indexing: Alkaloids (1977-1996)
Public MeSH Note: 97; STAUROSPORINE was indexed under ALKALOIDS 1977-96
Online Note: use STAUROSPORINE (NM) to search STAUROSPORINE 1980-96
History Note: 97; was STAUROSPORINE (NM) 1977-96
Date Established: 1997/01/01
Date of Entry: 1996/06/10
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Heterocyclic Compounds [D03]
- Alkaloids [D03.132]
  - Indole Alkaloids [D03.132.436]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Indoles [D03.633.100.473]
      - Carbazoles [D03.633.100.473.144]
        
        Carvedilol [D03.633.100.473.144.125]
        
        Ellipticines [D03.633.100.473.144.249]
        
        Ondansetron [D03.633.100.473.144.500]
        
        Staurosporine [D03.633.100.473.144.750]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Indoles [D03.633.100.473]
      - Indole Alkaloids [D03.633.100.473.402]
        
        Carbolines [D03.633.100.473.402.111]
        
        Harmala Alkaloids [D03.633.100.473.402.222]
        
        Lyngbya Toxins [D03.633.100.473.402.511]
        
        Oxindoles [D03.633.100.473.402.528]
        
        Physostigmine [D03.633.100.473.402.545]
        
        Psilocybin [D03.633.100.473.402.613]
        
        Secologanin Tryptamine Alkaloids [D03.633.100.473.402.681]
        
        Staurosporine [D03.633.100.473.402.750]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Indolizines [D03.633.100.496]
      - Indolizidines [D03.633.100.496.500]
        
        Indole Alkaloids [D03.633.100.496.500.500]
        
        Harmala Alkaloids [D03.633.100.496.500.500.384]
        
        Lyngbya Toxins [D03.633.100.496.500.500.448]
        
        Oxindoles [D03.633.100.496.500.500.511]
        
        Physostigmine [D03.633.100.496.500.500.545]
        
        Psilocybin [D03.633.100.496.500.500.613]
        
        Secologanin Tryptamine Alkaloids [D03.633.100.496.500.500.681]
        
        Staurosporine [D03.633.100.496.500.500.750]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 3-Ring [D03.633.300]
    - Carbazoles [D03.633.300.148]

Staurosporine Preferred

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