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Kininogen, High-Molecular-Weight MeSH Descriptor Data 2024


MeSH Heading
Kininogen, High-Molecular-Weight
Tree Number(s)
D12.644.276.812.654.350
D12.776.124.125.635.480
D12.776.467.812.654.350
D12.776.811.420.350
D23.119.630.480
D23.469.050.375.425.350
D23.529.812.654.350
Unique ID
D019679
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019679
Scope Note
A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)
Entry Version
KININOGEN HMW
Entry Term(s)
Fitzgerald Factor
HMWK
High Molecular Weight Kininogen
High Molecular Weight Kininogens
High-Molecular-Weight Kininogen
High-Molecular-Weight Kininogens
Kininogens, High Molecular Weight
Registry Number
0
Previous Indexing
Kininogens (1974-1997)
Public MeSH Note
98; see KININOGENS 1989-97
History Note
98; use KININOGENS 1989-97
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2006/07/05
Kininogen, High-Molecular-Weight Preferred
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