An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumor growth and metastasis.
Entry Term(s)
TSP-1
Previous Indexing
Membrane Glycoproteins (1993-1997)
Platelet Membrane Glycoproteins (1991-1993)
Public MeSH Note
98; THROMBOSPONDIN 1 was indexed under MEMBRANE GLYCOPROTEINS 1993-97& PLATELET MEMBRANE GLYCOPROTEINS 1991-93
An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumor growth and metastasis.
