MeSH Browser

MeSH Heading: Genistein
Tree Number(s): D03.383.663.283.266.450.400.375; D03.633.100.150.266.450.400.375
Unique ID: D019833
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019833
Scope Note: An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.
Entry Term(s): Genestein
Pharm Action: Anticarcinogenic Agents
Protein Kinase Inhibitors
Phytoestrogens
Registry Number: DH2M523P0H
Related Numbers: 446-72-0
Previous Indexing: Isoflavones (1976-1997)
Public MeSH Note: 98; GENISTEIN was indexed under ISOFLAVONES 1976-97
History Note: 98; use GENISTEIN (NM) 1980-97
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Genistein MeSH Descriptor Data 2024