Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

O(6)-Methylguanine-DNA Methyltransferase MeSH Descriptor Data 2025


MeSH Heading
O(6)-Methylguanine-DNA Methyltransferase
Tree Number(s)
D08.811.913.555.500.800.650
Unique ID
D019853
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019853
Scope Note
An enzyme that transfers methyl groups from O(6)-methylguanine, and other methylated moieties of DNA, to a cysteine residue in itself, thus repairing alkylated DNA in a single-step reaction. EC 2.1.1.63.
Entry Term(s)
DNA Repair Methyltransferase I
DNA Repair Methyltransferase II
Guanine-O(6)-Alkyltransferase
Methylated-DNA-Protein-Cysteine S-Methyltransferase
O(6)-AGT
O(6)-Alkylguanine-DNA Alkyltransferase
O(6)-MeG-DNA Methyltransferase
O(6)-Methylguanine DNA Transmethylase
O(6)-Methylguanine Methyltransferase
Registry Numbers
EC 2.1.1.63
0
Related Numbers
77271-19-3
CAS Type 1 Name
DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase
Previous Indexing
DNA (Cytosine-5-)-Methyltransferase (1978-1982)
Methyltransferases (1978-1997)
Public MeSH Note
98; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE was indexed under METHYLTRANSFERASES 1978-97 & DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1978-82
History Note
98; use O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE (NM) 1980-97
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2004/07/29
O(6)-Methylguanine-DNA Methyltransferase Preferred
DNA Repair Methyltransferase I Narrower
DNA Repair Methyltransferase II Narrower
page delivered in 0.121s