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Amino Acid Substitution MeSH Descriptor Data 2022


MeSH Heading
Amino Acid Substitution
Tree Number(s)
E05.393.420.601.035
G05.558.109
Unique ID
D019943
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019943
Scope Note
The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.
Previous Indexing
Amino Acid Sequence (1966-1997)
See Also
Mutagenesis, Site-Directed
Mutation, Missense
Public MeSH Note
98
History Note
98
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2016/01/15
Amino Acid Substitution Preferred
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