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RGS Proteins MeSH Descriptor Data 2022


MeSH Heading
RGS Proteins
Tree Number(s)
D12.644.360.325.150.750
D12.776.476.325.150.750
Unique ID
D020710
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020710
Annotation
do not confuse with GTP-BINDING PROTEIN REGULATORS; not the same as RGS tripeptide
Scope Note
A large family of evolutionarily conserved proteins that function as negative regulators of HETEROTRIMERIC GTP-BINDING PROTEINS. RGS PROTEINS act by increasing the GTPase activity of the G alpha subunit of a heterotrimeric GTP-binding protein, causing it to revert to its inactive (GDP-bound) form.
Entry Term(s)
RGS Protein (G-Protein Signaling)
Regulators of G-Protein Signaling Proteins
Pharm Action
GTP Phosphohydrolase Activators
Registry Number
0
Previous Indexing
Proteins (1989-1999)
Public MeSH Note
2000; RGS PROTEIN (G-PROTEIN SIGNALING) was indexed under PROTEINS 1997-1999
History Note
2000; for RGS PROTEIN (G-PROTEIN SIGNALING) use GTPASE-ACTIVATING PROTEINS (NM) 1997-1999
Date Established
2000/01/01
Date of Entry
1999/11/03
Revision Date
2015/11/24
RGS Proteins Preferred
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