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Eukaryotic Initiation Factor-5 MeSH Descriptor Data 2023


MeSH Heading
Eukaryotic Initiation Factor-5
Tree Number(s)
D12.644.360.325.150.300
D12.776.476.325.150.300
D12.776.835.725.868.750
Unique ID
D040061
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D040061
Scope Note
A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the hydrolysis of the bound GTP. The hydrolysis of GTP causes the release of EUKARYOTIC INITIATION FACTOR-2 and EUKARYOTIC INITIATION FACTOR-3 from the 40S subunit and the subsequent joining of the 60S ribosomal subunit to the 40S complex to form the functional 80S initiation complex
Entry Term(s)
EIF-5
Eukaryotic Peptide Initiation Factor-5
Peptide Initiation Factor EIF-5
Pharm Action
GTP Phosphohydrolase Activators
Registry Number
0
Previous Indexing
Peptide Initiation Factors (1982-2002)
Public MeSH Note
2003; EIF-5 (now EUKARYOTIC INITIATION FACTOR-5) was indexed under PEPTIDE INITIATION FACTORS 1982-2002
History Note
2003; use EUKARYOTIC INITIATION FACTOR-5 (NM) 1982-2002
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2015/11/23
Eukaryotic Initiation Factor-5 Preferred
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