MeSH Browser

MeSH Heading: Eukaryotic Initiation Factor-1
Tree Number(s): D12.776.835.725.868.124
Unique ID: D015977
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015977
Scope Note: A eukaryotic initiation factor that binds to 40S ribosomal subunits. Although initially considered a "non-essential" factor for eukaryotic transcription initiation, eukaryotic initiation factor-1 is now thought to play an important role in localizing RIBOSOMES at the initiation codon of MRNA.
Entry Term(s): EIF-1; Eukaryotic Peptide Initiation Factor-1; Peptide Initiation Factor EIF-1
Registry Number: 0
Previous Indexing: Peptide Initiation Factors (1978-1989)
Public MeSH Note: 2003; see EIF-1 1990-2002
History Note: 2003(1990)
Date Established: 1990/01/01
Date of Entry: 1989/10/18
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024412
Registry Number: 0
Scope Note: A eukaryotic initiation factor that binds to 40S ribosomal subunits. Although initially considered a "non-essential" factor for eukaryotic transcription initiation, eukaryotic initiation factor-1 is now thought to play an important role in localizing RIBOSOMES at the initiation codon of MRNA.
Terms: Eukaryotic Initiation Factor-1 Preferred Term
Term UI T047390
Date05/25/1989
LexicalTag NON
ThesaurusID NLM (1990); Eukaryotic Peptide Initiation Factor-1
Term UI T489240
Date04/11/2002
LexicalTag NON
ThesaurusID NLM (2003); Peptide Initiation Factor EIF-1
Term UI T047393
Date05/10/1989
LexicalTag ACX
ThesaurusID NLM (1990); EIF-1
Term UI T047389
Date01/01/1999
LexicalTag ACR
ThesaurusID NLM (1990)

Eukaryotic Initiation Factor-1 MeSH Descriptor Data 2024