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Vigabatrin MeSH Descriptor Data 2022


MeSH Heading
Vigabatrin
Tree Number(s)
D02.241.081.114.500.350.900
D12.125.190.350.900
Unique ID
D020888
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020888
Scope Note
An analogue of GAMMA-AMINOBUTYRIC ACID. It is an irreversible inhibitor of 4-AMINOBUTYRATE TRANSAMINASE, the enzyme responsible for the catabolism of GAMMA-AMINOBUTYRIC ACID and is used as an anticonvulsant. (From Martindale The Extra Pharmacopoeia, 31st ed)
Entry Term(s)
Sabril
Sabrilex
gamma-Vinyl-GABA
gamma-Vinyl-gamma-Aminobutyric Acid
Pharm Action
Anticonvulsants
Enzyme Inhibitors
GABA Agents
Registry Number
GR120KRT6K
Related Numbers
60643-86-9
CAS Type 1 Name
4-Amino-5-hexenoic Acid
Previous Indexing
Aminocaproic Acids (1981-1994)
GABA/analogs & derivatives (1979-1980)
GABA/analogs & derivatives (1994-1999)
Public MeSH Note
2000; VIGABATRIN was indexed under GABA/analogs & derivatives 1994-1999, AMINOCAPROIC ACIDS 1981-1994, & GABA/analogs 1979-1980
History Note
2000; use VIGABATRIN 1977-1999
Date Established
2000/01/01
Date of Entry
1999/11/04
Revision Date
2018/05/21
Vigabatrin Preferred
Sabrilex Narrower
Sabril Narrower
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