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Optic Atrophy, Autosomal Dominant MeSH Descriptor Data 2022


MeSH Heading
Optic Atrophy, Autosomal Dominant
Tree Number(s)
C10.292.700.225.500.100
C10.574.500.662.100
C11.270.564.100
C11.640.451.451.100
C16.320.290.564.100
C16.320.400.630.100
C18.452.660.665
Unique ID
D029241
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D029241
Scope Note
Dominant optic atrophy is a hereditary optic neuropathy causing decreased visual acuity, color vision deficits, a centrocecal scotoma, and optic nerve pallor (Hum. Genet. 1998; 102: 79-86). Mutations leading to this condition have been mapped to the OPA1 gene at chromosome 3q28-q29. OPA1 codes for a dynamin-related GTPase that localizes to mitochondria.
Entry Term(s)
Autosomal Dominant Optic Atrophy
Autosomal Dominant Optic Atrophy Kjer Type
Dominant Optic Atrophy
Kjer Type Optic Atrophy
Kjer's Optic Atrophy
Kjer-Type Optic Atrophy
Optic Atrophy 1
Optic Atrophy Type 1
Optic Atrophy, Hereditary, Autosomal Dominant
Optic Atrophy, Juvenile
Optic Atrophy, Kjer Type
Previous Indexing
Optic Atrophy (1971-2001)
Optic Atrophy, Hereditary (1989-2001)
Public MeSH Note
2002; see OPTIC ATROPHIES, HEREDITARY 2000-2001
History Note
2002; use OPTIC ATROPHIES, HEREDITARY 2000-2001
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2013/07/08
Optic Atrophy, Autosomal Dominant Preferred
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