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ADP-ribosyl Cyclase MeSH Descriptor Data 2023


MeSH Heading
ADP-ribosyl Cyclase
Tree Number(s)
D08.811.277.450.430.400.060
D08.811.913.400.725.115.660.060
Unique ID
D036541
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D036541
Scope Note
A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This enzyme generally catalyzes the hydrolysis of cADPR to ADP-RIBOSE, as well, and sometimes the synthesis of cyclic ADP-ribose 2' phosphate (2'-P-cADPR) from NADP.
Entry Term(s)
2'-P-ADPR Cyclase
2'-Phospho-adenosine Diphosphate Ribose Cyclase
ADP Ribose Cyclase
ADPR Cyclase
Adenosine Diphosphate Ribose Cyclase
Cyclic ADP-ribose Hydrolase
cADPR Hydrolase
Registry Number
EC 3.2.2.5
Related Numbers
EC 3.2.2.6
Previous Indexing
Antigens, Differentiation (1991-2002)
NAD+ Nucleosidase (1993-2002)
Public MeSH Note
2003; ADP-RIBOSYL CYCLASE was indexed under ANTIGENS, DIFFERENTIATION 1988-2002, NUCLEOSIDASES 1988-1997, and NAD+ NUCLEOSIDASES 1998-2002
History Note
2003; use CD38 ANTIGEN (NM) 1988-2002
Date Established
2003/01/01
Date of Entry
2002/07/02
Revision Date
2013/07/09
ADP-ribosyl Cyclase Preferred
Cyclic ADP-ribose Hydrolase Narrower
2'-P-ADPR Cyclase Narrower
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