MeSH Browser

MeSH Heading: Thyroid Hormone Receptors alpha
Tree Number(s): D12.776.624.664.700.830.500; D12.776.826.850.500
Unique ID: D037021
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D037021
Scope Note: High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRA gene (also known as NR1A1, THRA1, ERBA or ERBA1 gene) as several isoforms produced by alternative splicing.
Entry Version: THYROID HORMONE RECEPT ALPHA
Entry Term(s): ERBA1 Gene Products; NR1A1 Gene Products; Proto-Oncogene Proteins c-erbA; Receptors alpha, Thyroid Hormone; THRA Gene Products; Thyroid Hormone Receptor alpha-1; Thyroid Hormone Receptor alpha-2; c-erb A Protein; c-erb A Proteins; c-erbA Protein; c-erbA Proteins; c-erbA alpha; c-erbA alpha Protein; c-erbA-1 Protein; erbA Proto-Oncogene Products
Registry Numbers: 0
Previous Indexing: Receptors, Thyroid Hormone (1988-2002)
Public MeSH Note: 2003; see RECEPTORS, THYROID HORMONE 1994-2002
History Note: 2003; use RECEPTORS, THYROID HORMONE 1994-2002
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2015/06/23

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Neoplasm Proteins [D12.776.624]
    - Oncogene Proteins [D12.776.624.664]
      - Proto-Oncogene Proteins [D12.776.624.664.700]
        
        Receptors, Thyroid Hormone [D12.776.624.664.700.830]
        
        Thyroid Hormone Receptors alpha [D12.776.624.664.700.830.500]
        
        Thyroid Hormone Receptors beta [D12.776.624.664.700.830.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Receptors, Cytoplasmic and Nuclear [D12.776.826]
    - Receptors, Thyroid Hormone [D12.776.826.850]
      - Thyroid Hormone Receptors alpha [D12.776.826.850.500]
      - Thyroid Hormone Receptors beta [D12.776.826.850.750]

Thyroid Hormone Receptors alpha Preferred

Concept UI: M0018633
Registry Numbers: 0
Scope Note: High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRA gene (also known as NR1A1, THRA1, ERBA or ERBA1 gene) as several isoforms produced by alternative splicing.
Terms: Thyroid Hormone Receptors alpha Preferred Term
Term UI T427124
Date10/25/2000
LexicalTag NON
ThesaurusID NLM (2003); c-erbA Protein
Term UI T035656
Date03/19/1993
LexicalTag NON
ThesaurusID NLM (1994); c-erbA Proteins
Term UI T035657
Date03/19/1993
LexicalTag NON
ThesaurusID NLM (1994); Proto-Oncogene Proteins c-erbA
Term UI T035658
Date03/19/1993
LexicalTag NON
ThesaurusID NLM (1994); c-erb A Protein
Term UI T035659
Date02/02/1994
LexicalTag NON
ThesaurusID NLM (1995); c-erb A Proteins
Term UI T035660
Date02/02/1994
LexicalTag NON
ThesaurusID NLM (1995); erbA Proto-Oncogene Products
Term UI T035661
Date03/01/1994
LexicalTag NON
ThesaurusID NLM (1995); c-erbA alpha
Term UI T035673
Date03/14/1994
LexicalTag NON
ThesaurusID NLM (1995); THRA Gene Products
Term UI T478600
Date01/22/2002
LexicalTag NON
ThesaurusID NLM (2003); ERBA1 Gene Products
Term UI T478601
Date01/22/2002
LexicalTag NON
ThesaurusID NLM (2003); NR1A1 Gene Products
Term UI T478602
Date01/22/2002
LexicalTag NON
ThesaurusID NLM (2003); c-erbA-1 Protein
Term UI T490048
Date04/18/2002
LexicalTag NON
ThesaurusID NLM (2003); c-erbA alpha Protein
Term UI T490049
Date04/18/2002
LexicalTag NON
ThesaurusID NLM (2003); Receptors alpha, Thyroid Hormone
Term UI T492083
Date05/02/2002
LexicalTag NON
ThesaurusID NLM (2003)

Thyroid Hormone Receptor alpha-1 Narrower

Thyroid Hormone Receptor alpha-2 Narrower

Thyroid Hormone Receptors alpha MeSH Descriptor Data 2025