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Ribosomal Protein S6 Kinases, 70-kDa MeSH Descriptor Data 2025


MeSH Heading
Ribosomal Protein S6 Kinases, 70-kDa
Tree Number(s)
D08.811.913.696.620.682.700.862.249
D12.776.476.563.862.249
Unique ID
D038762
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D038762
Scope Note
A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.
Entry Term(s)
p70 S6 Kinase
p70s6k
Registry Numbers
EC 2.7.11.1
Previous Indexing
Ribosomal Protein S6 Kinases (1990-2002)
Public MeSH Note
2005; see RIBOSOMAL PROTEIN S6 KINASES, 70 KD 2003-2004; for P70 S6 KINASE & P70S6K see RIBOSOMAL PROTEIN S6 KINASES 1998-2002
History Note
2005(2003); for P70 S6 KINASE & P70S6K use RIBOSOMAL PROTEIN S6 KINASES 1998-2002
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2021/06/10
Ribosomal Protein S6 Kinases, 70-kDa Preferred
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