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This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.
Entry Term(s)
Antigens, CD49e
CD49e Antigen
CD49e Antigens
Integrin alphaF
Platelet Glycoprotein Ic
VLA-5 alpha Chain
alpha(5) Integrin
alpha5 Integrin
Registry Numbers
0
Previous Indexing
Antigens, CD (1996-2002)
Public MeSH Note
2003; INTEGRIN ALPHA5 was indexed under ANTIGENS, CD 1996-2002
This integrin alpha subunit combines with INTEGRIN BETA1 to form a receptor (INTEGRIN ALPHA5BETA1) that binds FIBRONECTIN and LAMININ. It undergoes posttranslational cleavage into a heavy and a light chain that are connected by disulfide bonds.