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Vascular Endothelial Growth Factor Receptor-1 MeSH Descriptor Data 2022


MeSH Heading
Vascular Endothelial Growth Factor Receptor-1
Tree Number(s)
D08.811.913.696.620.682.725.400.950.100
D12.776.476.568.400.950.100
D12.776.543.750.630.750.100
D12.776.543.750.750.400.910.100
Unique ID
D040281
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D040281
Scope Note
A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
Entry Version
VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPT 1
Entry Term(s)
FLT1 RTK
FLT1 Receptor Tyrosine Kinase
Proto-Oncogene Protein flt
VEGF Receptor flt-1 Protein
VEGF Receptor, FLT
VEGFR-1
fms-Like Tyrosine Kinase
Registry Number
EC 2.7.10.1
Previous Indexing
Proto-Oncogene Proteins (1991-2002)
Receptor Protein-Tyrosine Kinases (1991-2002)
Receptors, Growth Factor (1993-2002)
Public MeSH Note
2003; PROTO-ONCOGENE PROTEIN FLT (now VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1) was indexed under PROTO-ONCOGENE PROTEINS & RECEPTOR PROTEIN-TYROSINE KINASE 1991-2002
History Note
2003; use VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 (NM) 1990-2002; for FLK-1 RECEPTOR TYROSINE KINASE use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1993-2002
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2021/05/21
Vascular Endothelial Growth Factor Receptor-1 Preferred
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