MeSH Browser

MeSH Heading: beta-Lactams
Tree Number(s): D02.065.589.099; D02.886.108; D03.633.100.300
Unique ID: D047090
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D047090
Scope Note: Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
Entry Term(s): 4-Thia-1-Azabicyclo(3.2.0)Heptanes; 4-Thia-1-Azabicyclo(4.2.0)Octanes; beta-Lactam
Pharm Action: Anti-Bacterial Agents
Registry Numbers: 0
Previous Indexing: Lactams (1974-2004)
Public MeSH Note: 2005; see LACTAMS 1996-2004
History Note: 2005; use LACTAMS 1996-2004
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

beta-Lactams MeSH Descriptor Data 2025