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Clavulanic Acids MeSH Descriptor Data 2022


MeSH Heading
Clavulanic Acids
Tree Number(s)
D02.065.589.099.374
D03.633.100.300.374
Unique ID
D002969
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002969
Annotation
/biosyn permitted if by living matter
Scope Note
Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.
Pharm Action
Anti-Bacterial Agents
Enzyme Inhibitors
Registry Number
0
NLM Classification #
QV 350
Previous Indexing
Amides (1966-1973)
Amidohydrolases (1966-1978)
Lactams (1974-1982)
Penicillinase (1966-1978)
beta-Lactamases (1979-1982)
Public MeSH Note
83
History Note
83
Date Established
1983/01/01
Date of Entry
1982/05/05
Revision Date
2016/05/28
Clavulanic Acids Preferred
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