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Serotonin Plasma Membrane Transport Proteins MeSH Descriptor Data 2022


MeSH Heading
Serotonin Plasma Membrane Transport Proteins
Tree Number(s)
D12.776.157.530.450.625.311
D12.776.157.530.562.374.875
D12.776.157.530.937.624
D12.776.543.585.450.625.374
D12.776.543.585.562.374.875
D12.776.543.585.937.747
Unique ID
D050486
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050486
Scope Note
Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SEROTONIN UPTAKE INHIBITORS.
Entry Term(s)
5-Hydroxytryptamine Plasma Membrane Transport Protein
5HT Transporter
Neurotransmitter Transport Proteins, Serotonin-Specific
Neurotransmitter Transporters, Serotonin-Specific
Platelet Serotonin Transporter
SERT Proteins
SLC6A4 Protein
Serotonectin
Serotonin Plasma Membrane Transporter Proteins
Serotonin Transporter
Serotonin Transporter, Platelets
Sodium-Dependent Serotonin Transporter
Solute Carrier Family 6, Member 4 Protein
Registry Number
0
Previous Indexing
Carrier Proteins (1992-2004)
Membrane Glycoproteins (1992-2005)
Membrane Transport Proteins (2005)
Nerve Tissue Proteins (1992-2005)
See Also
Receptors, Serotonin
Public MeSH Note
2006; SEROTONIN TRANSPORTER was indexed under MEMBRANE TRANSPORT PROTEINS 2005, MEMBRANE GLYCOPROTEINS, NERVE TISSUE PROTEINS & MEMBRANE TRANSPORT PROTEINS 1992-2005, CARRIER PROTEINS 1992-2004; SEROTONECTIN was indexed under CARRIER PROTEINS 1983-2005
History Note
2006(1992)
Entry Combination
antagonists & inhibitors:Serotonin Uptake Inhibitors
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/02/26
Serotonin Plasma Membrane Transport Proteins Preferred
Solute Carrier Family 6, Member 4 Protein Narrower
Serotonectin Narrower
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