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3-Isopropylmalate Dehydrogenase MeSH Descriptor Data 2025
An NAD+ dependent enzyme that catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate to 3-carboxy-4-methyl-2-oxopentanoate. It is involved in the biosynthesis of VALINE; LEUCINE; and ISOLEUCINE.
Entry Term(s)
beta-IPM Dehydrogenase
beta-Isopropylmalate Dehydrogenase
Registry Numbers
EC 1.1.1.85
Related Numbers
9030-97-1
Public MeSH Note
2006; 3-ISOPROPYLMALATE DEHYDROGENASE was indexed under ALCOHOL OXIDOREDUCTASES 1981-2005, & under DICARBOXYLIC ACIDS 1970-1980
An NAD+ dependent enzyme that catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate to 3-carboxy-4-methyl-2-oxopentanoate. It is involved in the biosynthesis of VALINE; LEUCINE; and ISOLEUCINE.