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Ketol-Acid Reductoisomerase MeSH Descriptor Data 2022


MeSH Heading
Ketol-Acid Reductoisomerase
Tree Number(s)
D08.811.682.047.820.487
Unique ID
D050540
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050540
Scope Note
An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89.
Entry Term(s)
Acetohydroxy Acid Isomeroreductase
Alpha-Acetohydroxyacid Isomeroreductase
Dihydroxyisovalerate Dehydrogenase (Isomerizing)
Hydroxyacid Reductoisomerase
Isomeroreductase
Registry Number
EC 1.1.1.86
Related Numbers
9075-02-9
Public MeSH Note
2006; KETOL-ACID REDUCTOISOMERASE was indexed under ALCOHOL OXODOREDUCTASES 1983-2000, & under VALERATES 1970-1982
History Note
2006(1980); use VALERATES 1970-1979
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2013/07/08
Ketol-Acid Reductoisomerase Preferred
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