Smad3 Protein MeSH Descriptor Data 2023

MeSH Heading: Smad3 Protein
Tree Number(s): D12.644.360.024.334.500.300; D12.776.157.057.170.500.300; D12.776.260.713.500.300; D12.776.476.024.428.500.300; D12.776.744.741.875; D12.776.930.806.500.300
Unique ID: D051900
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051900
Scope Note: A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. Activated Smad3 can bind directly to DNA, and it regulates TRANSFORMING GROWTH FACTOR BETA and ACTIVIN signaling.
Entry Term(s): Madh3 Protein
Registry Number: 0
Public MeSH Note: 2006; SMAD3 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1996-2005
History Note: 2006(1996)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/02/18

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intracellular Signaling Peptides and Proteins [D12.644.360]
    - Adaptor Proteins, Signal Transducing [D12.644.360.024]
      - Smad Proteins [D12.644.360.024.334]
        
        Smad Proteins, Receptor-Regulated [D12.644.360.024.334.500]
        
        Smad1 Protein [D12.644.360.024.334.500.100]
        
        Smad2 Protein [D12.644.360.024.334.500.200]
        
        Smad3 Protein [D12.644.360.024.334.500.300]
        
        Smad5 Protein [D12.644.360.024.334.500.500]
        
        Smad8 Protein [D12.644.360.024.334.500.800]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Adaptor Proteins, Signal Transducing [D12.776.157.057]
      - Smad Proteins [D12.776.157.057.170]
        
        Smad Proteins, Receptor-Regulated [D12.776.157.057.170.500]
        
        Smad1 Protein [D12.776.157.057.170.500.100]
        
        Smad2 Protein [D12.776.157.057.170.500.200]
        
        Smad3 Protein [D12.776.157.057.170.500.300]
        
        Smad5 Protein [D12.776.157.057.170.500.500]
        
        Smad8 Protein [D12.776.157.057.170.500.800]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - DNA-Binding Proteins [D12.776.260]
    - Smad Proteins [D12.776.260.713]
      - Smad Proteins, Receptor-Regulated [D12.776.260.713.500]
        
        Smad1 Protein [D12.776.260.713.500.100]
        
        Smad3 Protein [D12.776.260.713.500.300]
        
        Smad5 Protein [D12.776.260.713.500.500]
        
        Smad8 Protein [D12.776.260.713.500.800]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Adaptor Proteins, Signal Transducing [D12.776.476.024]
      - Smad Proteins [D12.776.476.024.428]
        
        Smad Proteins, Receptor-Regulated [D12.776.476.024.428.500]
        
        Smad1 Protein [D12.776.476.024.428.500.100]
        
        Smad2 Protein [D12.776.476.024.428.500.200]
        
        Smad3 Protein [D12.776.476.024.428.500.300]
        
        Smad5 Protein [D12.776.476.024.428.500.500]
        
        Smad8 Protein [D12.776.476.024.428.500.800]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Phosphoproteins [D12.776.744]
    - Smad Proteins, Receptor-Regulated [D12.776.744.741]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Transcription Factors [D12.776.930]
    - Smad Proteins [D12.776.930.806]
      - Smad Proteins, Receptor-Regulated [D12.776.930.806.500]
        
        Smad1 Protein [D12.776.930.806.500.100]
        
        Smad2 Protein [D12.776.930.806.500.200]
        
        Smad3 Protein [D12.776.930.806.500.300]
        
        Smad5 Protein [D12.776.930.806.500.500]
        
        Smad8 Protein [D12.776.930.806.500.800]

Smad3 Protein Preferred

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