MeSH Browser

MeSH Heading: Apolipoprotein C-II
Tree Number(s): D10.532.091.400.750; D12.776.070.400.400.750; D12.776.521.120.400.750
Unique ID: D053304
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053304
Scope Note: A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.
Entry Term(s): Apo C-II; ApoC2; Apolipoprotein C-2; Apolipoprotein CII; Apoprotein C-II
Previous Indexing: Apolipoproteins C (1977-2006)
See Also: Hyperlipoproteinemia Type I
Public MeSH Note: 2007; APOLIPOPROTEIN C-II was indexed under APOLIPOPROTEINS C 1984-2006 & under APOLIPOPROTEINS 1978-1984
History Note: 2007; use APOLIPOPROTEIN C-II (NM) 1978-2006
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2009/07/06

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0066119
Scope Note: A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.
Terms: Apolipoprotein C-II Preferred Term
Term UI T096122
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Apo C-II
Term UI T096117
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); ApoC2
Term UI T096118
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Apolipoprotein C-2
Term UI T096119
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Apolipoprotein CII
Term UI T096120
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Apoprotein C-II
Term UI T096121
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007)

Apolipoprotein C-II MeSH Descriptor Data 2024