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Matrix Metalloproteinase 16 MeSH Descriptor Data 2024


MeSH Heading
Matrix Metalloproteinase 16
Tree Number(s)
D08.811.277.656.300.480.525.300.600
D08.811.277.656.675.374.525.300.750
Unique ID
D053513
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053513
Scope Note
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES. Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen of MATRIX METALLOPROTEINASE 2.
Entry Term(s)
MMP-16 Metalloproteinase
MMP-X2 Protein
MMP16 Metalloproteinase
MT3-MMP
MT3-Matrix Metalloproteinase
Membrane-Type 3 Matrix Metalloproteinase
Membrane-Type Matrix Metalloproteinase 3
Membrane-Type-3 Matrix Metalloproteinase
Registry Number
EC 3.4.24.-
Public MeSH Note
2007; MATRIX METALLOPROTEINASE 16 was indexed under MATRIX METALLOPROTEINASES 2006 & under METALLOENDOPEPTIDASES 2005
History Note
2007(2005)
Entry Combination
antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2012/07/03
Matrix Metalloproteinase 16 Preferred
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