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Matrix Metalloproteinase 14 MeSH Descriptor Data 2024


MeSH Heading
Matrix Metalloproteinase 14
Tree Number(s)
D08.811.277.656.300.480.525.300.500
D08.811.277.656.675.374.525.300.500
Unique ID
D053511
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053511
Scope Note
A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15.
Entry Term(s)
MMP-14 Metalloproteinase
MMP-X1 Protein
MMP14 Metalloproteinase
MT-MMP-1
MT1-MMP
MT1-Matrix Metalloproteinase
Membrane-Type 1 Matrix Metalloproteinase
Membrane-Type Matrix Metalloproteinase 1
Registry Number
EC 3.4.24.80
Public MeSH Note
2007; MATRIX METALLOPROTEINASE 14 was indexed under MATRIX METALLOPROTEINASES 2006 & under METALLOENDOPEPTIDASES 1994-2005
History Note
2007(1994)
Entry Combination
antagonists & inhibitors:Matrix Metalloproteinase Inhibitors
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2012/07/03
Matrix Metalloproteinase 14 Preferred
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