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Interleukin-1 Receptor Accessory Protein MeSH Descriptor Data 2022


MeSH Heading
Interleukin-1 Receptor Accessory Protein
Tree Number(s)
D12.776.543.750.705.852.420.300.249
Unique ID
D053577
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053577
Annotation
Do not confuse with INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN
Scope Note
A protein that takes part in the formation of active interleukin-1 receptor complex. It binds specifically to INTERLEUKIN-1 and the INTERLEUKIN-1 RECEPTOR TYPE I at the cell surface to form a heterotrimeric complex that brings its cytoplasmic domain into contact with the cytoplasm domain of the TYPE-I INTERLEUKIN-1 RECEPTOR. Activation of intracellular signal transduction pathways from the receptor is believed to be driven by this form of cytoplasmic interaction.
Entry Term(s)
IL-1RAcP
Registry Number
0
Public MeSH Note
2007; Interleukin-1 Receptor Accessory Protein was indexed under RECEPTORS, INTERLEUKIN-1 2006 & under PROTEINS 1996-2006
History Note
2007(1996)
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2009/07/20
Interleukin-1 Receptor Accessory Protein Preferred
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