MeSH Browser

MeSH Heading: Receptors, Interleukin-1 Type II
Tree Number(s): D12.776.543.750.705.852.420.300.750
Unique ID: D053574
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053574
Scope Note: An interleukin-1 receptor subtype that competes with the INTERLEUKIN-1 RECEPTOR TYPE I for binding to INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The interleukin-1 type II receptor appears to lack signal transduction capability. Therefore it may act as a decoy receptor that modulates the activity of its ligands. Both membrane-bound and soluble forms of the receptor have been identified.
Entry Term(s): Antigens, CDw121b; CDw121b Antigens; Interleukin-1 Receptor Type II; Interleukin-1 Receptor, Type 2; Interleukin-1 Receptors Type II
Public MeSH Note: 2007; see RECEPTORS, INTERLEUKIN-1 1996-2006
History Note: 2007(1996)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M0259861
Scope Note: An interleukin-1 receptor subtype that competes with the INTERLEUKIN-1 RECEPTOR TYPE I for binding to INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The interleukin-1 type II receptor appears to lack signal transduction capability. Therefore it may act as a decoy receptor that modulates the activity of its ligands. Both membrane-bound and soluble forms of the receptor have been identified.
Terms: Receptors, Interleukin-1 Type II Preferred Term
Term UI T665931
Date02/07/2006
LexicalTag NON
ThesaurusID NLM (2007); Antigens, CDw121b
Term UI T052399
Date01/26/1995
LexicalTag NON
ThesaurusID NLM (1996); CDw121b Antigens
Term UI T052400
Date01/26/1995
LexicalTag NON
ThesaurusID NLM (1996); Interleukin-1 Receptor Type II
Term UI T289866
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Interleukin-1 Receptor, Type 2
Term UI T289863
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Interleukin-1 Receptors Type II
Term UI T289864
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007)

Receptors, Interleukin-1 Type II MeSH Descriptor Data 2024