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A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.
Entry Term(s)
Alkyl Hydroperoxide Reductase
Alkyl Hydroperoxide Reductase C
Alkyl Hydroperoxide Reductase D
Alkylhydroperoxide Reductase
Peroxidoxin
Peroxiredoxin
Peroxiredoxin 1
Peroxiredoxin 2
Peroxiredoxin 4
Peroxiredoxin 5
Peroxiredoxin I
Peroxiredoxin II
Peroxiredoxin IV
Peroxiredoxin V
Peroxiredoxin-4
Protector Protein (Mixed-Function Oxidase Systems)
Thiol-Specific Antioxidant Protein
Thioredoxin Peroxidase
Thioredoxin Peroxidase 1
Thioredoxin Peroxidase 2
Thioredoxin Peroxidase PMP20
Thioredoxin-Dependent Peroxide Reductase 1
Thioredoxin-Dependent Peroxide Reductase 2
Registry Numbers
EC 1.11.1.15
EC 1.11.1.15
EC 1.11.1.15
EC 1.11.1.15
EC 1.11.1.15
EC 1.11.1.15
EC 1.11.1.15
Related Numbers
EC 1.11.1.15
Public MeSH Note
2008; PEROXIDOXIN (now PEROXIDOXINS) was indexed under PEROXIDASES 2000-2007 & under OXIDOREDUCTASES 1988-1999; PEROXIREDOXIN IV was indexed under PEROXIDASES 2000-2007
A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.