Bone Morphogenetic Protein 15 MeSH Descriptor Data 2025

MeSH Heading: Bone Morphogenetic Protein 15
Tree Number(s): D12.644.276.954.200.900; D12.644.276.954.300.049; D12.776.467.942.200.900; D12.776.467.942.300.049; D23.529.942.200.900; D23.529.942.300.049
Unique ID: D055430
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D055430
Scope Note: A protein that plays a role in GRANULOSA CELLS where it regulates folliculogenesis. Mutations in the gene for bone morphogenetic protein 15 are linked to reproductive abnormalities such as PREMATURE OVARIAN FAILURE.
Entry Term(s): BMP-15; GDF-9 Related Factor; GDF-9-Related Protein; GDF-9B; Growth Differentiation Factor 9B
Registry Numbers: 0
Public MeSH Note: 2009; BONE MORPHOGENETIC PROTEIN 15 was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2003-2008, & under GROWTH SUBSTANCES 1993-2002
History Note: 2009(1993) for BONE MORPHOGENETIC PROTEIN 15 use GROWTH DIFFERENTIATION FACTOR 9 1993-2008
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intercellular Signaling Peptides and Proteins [D12.644.276]
    - TGF-beta Superfamily Proteins [D12.644.276.954]
      - Bone Morphogenetic Proteins [D12.644.276.954.200]
        
        Bone Morphogenetic Protein 1 [D12.644.276.954.200.100]
        
        Bone Morphogenetic Protein 2 [D12.644.276.954.200.200]
        
        Bone Morphogenetic Protein 3 [D12.644.276.954.200.300]
        
        Bone Morphogenetic Protein 4 [D12.644.276.954.200.400]
        
        Bone Morphogenetic Protein 5 [D12.644.276.954.200.500]
        
        Bone Morphogenetic Protein 6 [D12.644.276.954.200.600]
        
        Bone Morphogenetic Protein 7 [D12.644.276.954.200.700]
        
        Bone Morphogenetic Protein 15 [D12.644.276.954.200.900]
        
        Growth Differentiation Factor 2 [D12.644.276.954.200.910]
        
        Growth Differentiation Factor 10 [D12.644.276.954.200.950]

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intercellular Signaling Peptides and Proteins [D12.644.276]
    - TGF-beta Superfamily Proteins [D12.644.276.954]
      - Growth Differentiation Factors [D12.644.276.954.300]
        
        Bone Morphogenetic Protein 15 [D12.644.276.954.300.049]
        
        Growth Differentiation Factor 1 [D12.644.276.954.300.100]
        
        Growth Differentiation Factor 2 [D12.644.276.954.300.200]
        
        Growth Differentiation Factor 3 [D12.644.276.954.300.300]
        
        Growth Differentiation Factor 5 [D12.644.276.954.300.500]
        
        Growth Differentiation Factor 6 [D12.644.276.954.300.600]
        
        Growth Differentiation Factor 9 [D12.644.276.954.300.800]
        
        Growth Differentiation Factor 10 [D12.644.276.954.300.900]
        
        Growth Differentiation Factor 15 [D12.644.276.954.300.915]
        
        Myostatin [D12.644.276.954.300.925]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - TGF-beta Superfamily Proteins [D12.776.467.942]
      - Bone Morphogenetic Proteins [D12.776.467.942.200]
        
        Bone Morphogenetic Protein 1 [D12.776.467.942.200.100]
        
        Bone Morphogenetic Protein 2 [D12.776.467.942.200.200]
        
        Bone Morphogenetic Protein 3 [D12.776.467.942.200.300]
        
        Bone Morphogenetic Protein 4 [D12.776.467.942.200.400]
        
        Bone Morphogenetic Protein 5 [D12.776.467.942.200.500]
        
        Bone Morphogenetic Protein 6 [D12.776.467.942.200.600]
        
        Bone Morphogenetic Protein 7 [D12.776.467.942.200.700]
        
        Bone Morphogenetic Protein 15 [D12.776.467.942.200.900]
        
        Growth Differentiation Factor 2 [D12.776.467.942.200.910]
        
        Growth Differentiation Factor 10 [D12.776.467.942.200.950]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - TGF-beta Superfamily Proteins [D12.776.467.942]
      - Growth Differentiation Factors [D12.776.467.942.300]
        
        Bone Morphogenetic Protein 15 [D12.776.467.942.300.049]
        
        Growth Differentiation Factor 1 [D12.776.467.942.300.100]
        
        Growth Differentiation Factor 2 [D12.776.467.942.300.200]
        
        Growth Differentiation Factor 3 [D12.776.467.942.300.300]
        
        Growth Differentiation Factor 5 [D12.776.467.942.300.500]
        
        Growth Differentiation Factor 6 [D12.776.467.942.300.600]
        
        Growth Differentiation Factor 9 [D12.776.467.942.300.800]
        
        Growth Differentiation Factor 10 [D12.776.467.942.300.900]
        
        Growth Differentiation Factor 15 [D12.776.467.942.300.915]
        
        Myostatin [D12.776.467.942.300.925]

Biological Factors [D23]
- Intercellular Signaling Peptides and Proteins [D23.529]
  - TGF-beta Superfamily Proteins [D23.529.942]
    - Bone Morphogenetic Proteins [D23.529.942.200]

Biological Factors [D23]
- Intercellular Signaling Peptides and Proteins [D23.529]
  - TGF-beta Superfamily Proteins [D23.529.942]
    - Growth Differentiation Factors [D23.529.942.300]

Bone Morphogenetic Protein 15 Preferred

Concept UI: M0355426
Registry Numbers: 0
Scope Note: A protein that plays a role in GRANULOSA CELLS where it regulates folliculogenesis. Mutations in the gene for bone morphogenetic protein 15 are linked to reproductive abnormalities such as PREMATURE OVARIAN FAILURE.
Terms: Bone Morphogenetic Protein 15 Preferred Term
Term UI T713159
Date01/18/2008
LexicalTag NON
ThesaurusID NLM (2009); BMP-15
Term UI T421278
Date08/10/2000
LexicalTag ABB
ThesaurusID NLM (2009); GDF-9 Related Factor
Term UI T713391
Date01/23/2008
LexicalTag ABX
ThesaurusID NLM (2009); GDF-9-Related Protein
Term UI T713392
Date01/23/2008
LexicalTag ABX
ThesaurusID NLM (2009); GDF-9B
Term UI T404855
Date01/12/2000
LexicalTag ABB
ThesaurusID NLM (2009); Growth Differentiation Factor 9B
Term UI T713390
Date01/23/2008
LexicalTag NON
ThesaurusID NLM (2009)

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