A growth differentiation factor that may play a role in maintaining the undifferentiated state of PLURIPOTENT STEM CELLS by inhibiting the actions of BONE MORPHOGENETIC PROTEINS. Differentiation factor 3 is also considered a nodal signaling ligand that influences the genesis of left-right asymmetry.
Entry Term(s)
GDF-3
Public MeSH Note
2009; GROWTH DIFFERENTIATION FACTOR 3 was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2003-2008, & under GROWTH SUBSTANCES 1993-2002
A growth differentiation factor that may play a role in maintaining the undifferentiated state of PLURIPOTENT STEM CELLS by inhibiting the actions of BONE MORPHOGENETIC PROTEINS. Differentiation factor 3 is also considered a nodal signaling ligand that influences the genesis of left-right asymmetry.
