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A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
Entry Term(s)
Agnogenic Myeloid Metaplasia
Bone Marrow Fibrosis
Chronic Idiopathic Myelofibrosis
Fibrosis, Bone Marrow
Idiopathic Myelofibrosis
Myelofibrosis
Myelofibrosis With Myeloid Metaplasia
Myeloid Metaplasia
Myelosclerosis
Myelosis, Nonleukemic
NLM Classification #
WH 385
Previous Indexing
Myelofibrosis (1963-2008)
Public MeSH Note
2009; see MYELOID METAPLASIA or MYELOFIBROSIS 1975-2008
A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.