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Class Ia Phosphatidylinositol 3-Kinase MeSH Descriptor Data 2025


MeSH Heading
Class Ia Phosphatidylinositol 3-Kinase
Tree Number(s)
D08.811.913.696.620.500.100.100.100
D08.811.913.696.620.500.200.100.100
D12.776.476.556.100.100.100
D12.776.476.556.200.100.100
Unique ID
D058543
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D058543
Scope Note
A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the heterodimerization of a p110 catalytic and a p85, p55, or p50 regulatory subunit. This subclass of enzymes is a downstream target of TYROSINE KINASE RECEPTORS and G PROTEIN-COUPLED RECEPTORS.
Entry Term(s)
Class Ia Phosphatidylinositol 3-Kinase, p110alpha Subunit
Class Ia Phosphatidylinositol 3-Kinase, p110beta Subunit
Class Ia Phosphatidylinositol 3-Kinase, p110delta Subunit
Class Ia Phosphatidylinositol 3-Kinase, p50alpha Subunit
Class Ia Phosphatidylinositol 3-Kinase, p55alpha Subunit
Class Ia Phosphatidylinositol 3-Kinase, p55gamma Subunit
Class Ia Phosphatidylinositol 3-Kinase, p85alpha Subunit
Class Ia Phosphatidylinositol 3-Kinase, p85beta Subunit
Class Ia Phosphatidylinositol 3-Kinases
Class Ia Phosphatidylinositol 3-kinase, Regulatory, alpha Polypeptide
Class Ia Phosphatidylinositol 3-kinase, Regulatory, beta Polypeptide
Class Ia Phosphatidylinositol 3-kinase, Regulatory, gamma Polypeptide
Phosphatidylinositol 3-Kinase, Class Ia
Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide
Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide
Phosphoinositide-3-Kinase, Catalytic, delta Polypeptide
Phosphoinositide-3-Kinase, Regulatory Subunit 1
Phosphoinositide-3-Kinase, Regulatory Subunit 2
Phosphoinositide-3-Kinase, Regulatory Subunit 3
alpha-P85 Subunit, PI-3K
p110alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase
p110beta Subunit, Class Ia Phosphatidylinositol 3-Kinase
p110delta Subunit, Class Ia Phosphatidylinositol 3-Kinase
p50alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase
p55alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase
p55gamma Subunit, Class Ia Phosphatidylinositol 3-Kinase
p85alpha Subunit, Class Ia Phosphatidylinositol 3-Kinase
p85beta Subunit, Class Ia Phosphatidylinositol 3-Kinase
Registry Numbers
EC 2.7.1.137
EC 2.7.1.154
EC 2.7.1.154
EC 2.7.1.154
0
EC 2.7.1.137
EC 2.7.1.137
Related Numbers
EC 2.7.1.137
EC 2.7.1.154
Previous Indexing
Phosphatidylinositol 3-Kinases (1998-2010)
Public MeSH Note
2011; for ALPHA-P85 SUBUNIT, PI-3K see PHOSPHATIDYLINOSITOL 3-KINASE 1998-2010
History Note
2011; for ALPHA-P85 SUBUNIT, PI-3K use PHOSPHATIDYLINOSITOL 3-KINASES 1998-2010
Date Established
2011/01/01
Date of Entry
2010/06/25
Revision Date
2021/05/21
Class Ia Phosphatidylinositol 3-Kinase Preferred
Class Ia Phosphatidylinositol 3-Kinase, p110alpha Subunit Narrower
Class Ia Phosphatidylinositol 3-Kinase, p110beta Subunit Narrower
Class Ia Phosphatidylinositol 3-Kinase, p110delta Subunit Narrower
Class Ia Phosphatidylinositol 3-Kinase, p85alpha Subunit Narrower
Class Ia Phosphatidylinositol 3-Kinase, p85beta Subunit Narrower
Class Ia Phosphatidylinositol 3-Kinase, p55gamma Subunit Narrower
Class Ia Phosphatidylinositol 3-Kinase, p55alpha Subunit Narrower
Class Ia Phosphatidylinositol 3-Kinase, p50alpha Subunit Narrower
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