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Peroxisomal Bifunctional Enzyme MeSH Descriptor Data 2022


MeSH Heading
Peroxisomal Bifunctional Enzyme
Tree Number(s)
D08.811.399.475.400.349.500
D08.811.520.241.300.250.750
D08.811.641.781
D08.811.682.047.820.150.207.500
Unique ID
D063994
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D063994
Scope Note
A monomeric protein found in liver peroxisomes that contains two enzymatically active domains; an enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase domain, and an (S)-3-hydroxyacyl-CoA dehydrogenase domain. The enzyme is stereospecific with regards to how cis and trans double bonds are metabolized. It is complemented by PEROXISOMAL MULTIFUNCTIONAL PROTEIN-2, which has the opposite stereospecificity.
Entry Term(s)
2-Enoyl-CoA Hydratase, 3-Hydroxyacyl-CoA Dehydrogenase-delta 3, delta 2-Enoyl-CoA Isomerase
Enoyl-CoA Hydratase-3-Hydroxyacyl-CoA Dehydrogenase
L-Bifunctional Enzyme
L-Peroxisomal Bifunctional Enzyme
Peroxisomal Hydratase-Dehydrogenase-Epimerase
Peroxisomal Multifunctional beta-Oxidation Protein
Peroxisomal Trifunctional Enzyme
Peroxisomal-Bifunctional Enzymes
Registry Number
EC 4.2.1.17
Related Numbers
EC 1.1.1.35
EC 5.3.3.8
Public MeSH Note
2014; PEROXIISOMAL-BIFUNCTIONAL ENZYME was indexed under ENOYL-COA-HYDRATASE, ISOMERASES, 3-HYDROXYACYL COA DEHYDROGENASES, and MULTIENZYME COMPLEXES 1986-2013
History Note
2014
Date Established
2014/01/01
Date of Entry
2013/07/09
Revision Date
2016/04/18
Peroxisomal Bifunctional Enzyme Preferred
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