Minichromosome Maintenance Complex Component 3 MeSH Descriptor Data 2024

MeSH Heading: Minichromosome Maintenance Complex Component 3
Tree Number(s): D08.811.277.040.025.159.186.300; D08.811.399.340.186.300; D12.776.167.409.300; D12.776.660.235.500.300; D12.776.664.235.750.300
Unique ID: D064126
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064126
Scope Note: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL, which provide targeting of the protein complex. In addition, acetylation of this protein may play a role in regulating of DNA replication and cell cycle progression.
Entry Term(s): DNA Polymerase alpha Holoenzyme-associated Protein P1; DNA Replication Licensing Factor MCM3; RLF Subunit beta
Registry Number: EC 3.6.4.12
Previous Indexing: Cell Cycle Proteins (1990-2013); DNA-Binding Proteins (1990-2013); Nuclear Proteins (1990-2013)
Public MeSH Note: 2014
History Note: 2014
Date Established: 2014/01/01
Date of Entry: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Acid Anhydride Hydrolases [D08.811.277.040]
      - Adenosine Triphosphatases [D08.811.277.040.025]
        
        DNA Helicases [D08.811.277.040.025.159]
        
        Minichromosome Maintenance Proteins [D08.811.277.040.025.159.186]
        
        Minichromosome Maintenance Complex Component 2 [D08.811.277.040.025.159.186.200]
        
        Minichromosome Maintenance Complex Component 3 [D08.811.277.040.025.159.186.300]
        
        Minichromosome Maintenance Complex Component 4 [D08.811.277.040.025.159.186.400]
        
        Minichromosome Maintenance Complex Component 5 [D08.811.277.040.025.159.186.500]
        
        Minichromosome Maintenance Complex Component 6 [D08.811.277.040.025.159.186.600]
        
        Minichromosome Maintenance Complex Component 7 [D08.811.277.040.025.159.186.700]
        
        Minichromosome Maintenance Complex Component 8 [D08.811.277.040.025.159.186.800]
        
        Minichromosome Maintenance Complex Component 9 [D08.811.277.040.025.159.186.900]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Isomerases [D08.811.399]
    - DNA Helicases [D08.811.399.340]
      - Minichromosome Maintenance Proteins [D08.811.399.340.186]
        
        Minichromosome Maintenance Complex Component 2 [D08.811.399.340.186.200]
        
        Minichromosome Maintenance Complex Component 3 [D08.811.399.340.186.300]
        
        Minichromosome Maintenance Complex Component 4 [D08.811.399.340.186.400]
        
        Minichromosome Maintenance Complex Component 5 [D08.811.399.340.186.500]
        
        Minichromosome Maintenance Complex Component 6 [D08.811.399.340.186.600]
        
        Minichromosome Maintenance Complex Component 7 [D08.811.399.340.186.700]
        
        Minichromosome Maintenance Complex Component 8 [D08.811.399.340.186.800]
        
        Minichromosome Maintenance Complex Component 9 [D08.811.399.340.186.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Cell Cycle Proteins [D12.776.167]
    - Minichromosome Maintenance Proteins [D12.776.167.409]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nuclear Proteins [D12.776.660]
    - Chromosomal Proteins, Non-Histone [D12.776.660.235]
      - Minichromosome Maintenance Proteins [D12.776.660.235.500]
        
        Minichromosome Maintenance 1 Protein [D12.776.660.235.500.100]
        
        Minichromosome Maintenance Complex Component 2 [D12.776.660.235.500.200]
        
        Minichromosome Maintenance Complex Component 3 [D12.776.660.235.500.300]
        
        Minichromosome Maintenance Complex Component 4 [D12.776.660.235.500.400]
        
        Minichromosome Maintenance Complex Component 5 [D12.776.660.235.500.500]
        
        Minichromosome Maintenance Complex Component 6 [D12.776.660.235.500.600]
        
        Minichromosome Maintenance Complex Component 7 [D12.776.660.235.500.700]
        
        Minichromosome Maintenance Complex Component 8 [D12.776.660.235.500.800]
        
        Minichromosome Maintenance Complex Component 9 [D12.776.660.235.500.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Nucleoproteins [D12.776.664]
    - Chromosomal Proteins, Non-Histone [D12.776.664.235]
      - Minichromosome Maintenance Proteins [D12.776.664.235.750]
        
        Minichromosome Maintenance 1 Protein [D12.776.664.235.750.100]
        
        Minichromosome Maintenance Complex Component 2 [D12.776.664.235.750.200]
        
        Minichromosome Maintenance Complex Component 3 [D12.776.664.235.750.300]
        
        Minichromosome Maintenance Complex Component 4 [D12.776.664.235.750.400]
        
        Minichromosome Maintenance Complex Component 5 [D12.776.664.235.750.500]
        
        Minichromosome Maintenance Complex Component 6 [D12.776.664.235.750.600]
        
        Minichromosome Maintenance Complex Component 7 [D12.776.664.235.750.700]
        
        Minichromosome Maintenance Complex Component 8 [D12.776.664.235.750.800]
        
        Minichromosome Maintenance Complex Component 9 [D12.776.664.235.750.900]

Minichromosome Maintenance Complex Component 3 Preferred

Concept UI: M0579722
Registry Number: EC 3.6.4.12
Scope Note: A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL, which provide targeting of the protein complex. In addition, acetylation of this protein may play a role in regulating of DNA replication and cell cycle progression.
Terms: Minichromosome Maintenance Complex Component 3 Preferred Term
Term UI T834551
Date12/19/2012
LexicalTag NON
ThesaurusID NLM (2014); DNA Replication Licensing Factor MCM3
Term UI T834552
Date12/19/2012
LexicalTag ABX
ThesaurusID NLM (2014); RLF Subunit beta
Term UI T834554
Date12/19/2012
LexicalTag ABX
ThesaurusID NLM (2014); DNA Polymerase alpha Holoenzyme-associated Protein P1
Term UI T834553
Date12/19/2012
LexicalTag ABX
ThesaurusID NLM (2014)

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