MeSH Browser

MeSH Heading: Membrane Cofactor Protein
Tree Number(s): D12.776.124.486.274.920.124; D12.776.543.750.705.833.124
Unique ID: D051916
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051916
Scope Note: A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
Entry Term(s): Antigens, CD46; CD46 Antigen; CD46 Antigens; Trophoblast-Leukocyte Common Antigen
Pharm Action: Immunologic Factors
Registry Numbers: 0
Public MeSH Note: 2018; see ANTIGENS, CD46 1987-2017; MEMBRANE COFACTOR PROTEIN was indexed under MEMBRANE GLYCOPROTEINS 1988-2005; under ANTIGENS, CD 1992-2005; under ANTIGENS, DIFFERENTIATION 1990-1991; and under MEMBRANE PROTEINS 1987
History Note: 2018 (1987)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M0148714
Registry Numbers: 0
Scope Note: A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
Terms: Membrane Cofactor Protein Preferred Term
Term UI T178719
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); CD46 Antigen
Term UI T178713
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Trophoblast-Leukocyte Common Antigen
Term UI T633848
Date03/21/2005
LexicalTag NON
ThesaurusID NLM (2006); Antigens, CD46
Term UI T633858
Date03/21/2005
LexicalTag NON
ThesaurusID NLM (2006); CD46 Antigens
Term UI T636286
Date04/12/2005
LexicalTag NON
ThesaurusID NLM (2006)

Membrane Cofactor Protein MeSH Descriptor Data 2025