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Membrane Cofactor Protein MeSH Descriptor Data 2025
A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
2018; see ANTIGENS, CD46 1987-2017; MEMBRANE COFACTOR PROTEIN was indexed under MEMBRANE GLYCOPROTEINS 1988-2005; under ANTIGENS, CD 1992-2005; under ANTIGENS, DIFFERENTIATION 1990-1991; and under MEMBRANE PROTEINS 1987
A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.